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Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors
The development of isoform selective inhibitors of the carbonic anhydrase (CA; EC 4.2.1.1) enzymes represents the key approach for the successful development of druggable small molecules. Herein we report a series of new benzenesulfamide derivatives (-NH-SO(2)NH(2)) bearing the 1-benzhydrylpiperazin...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151984/ https://www.ncbi.nlm.nih.gov/pubmed/28672822 http://dx.doi.org/10.3390/molecules22071049 |