Fluorination of Naturally Occurring N(6)-Benzyladenosine Remarkably Increased Its Antiviral Activity and Selectivity

Recently, we demonstrated that the natural cytokinin nucleosides N(6)-isopentenyladenosine (iPR) and N(6)-benzyladenosine (BAPR) exert a potent and selective antiviral effect on the replication of human enterovirus 71. In order to further characterize the antiviral profile of this class of compounds...

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Detalles Bibliográficos
Autores principales: Oslovsky, Vladimir E., Drenichev, Mikhail S., Sun, Liang, Kurochkin, Nikolay N., Kunetsky, Vladislav E., Mirabelli, Carmen, Neyts, Johan, Leyssen, Pieter, Mikhailov, Sergey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152005/
https://www.ncbi.nlm.nih.gov/pubmed/28726764
http://dx.doi.org/10.3390/molecules22071219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152005/
https://www.ncbi.nlm.nih.gov/pubmed/28726764
http://dx.doi.org/10.3390/molecules22071219

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