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The Influence of Glycosylation of Natural and Synthetic Prenylated Flavonoids on Binding to Human Serum Albumin and Inhibition of Cyclooxygenases COX-1 and COX-2

The synthesis of different classes of prenylated aglycones (α,β-dihydroxanthohumol (2) and (Z)-6,4’-dihydroxy-4-methoxy-7-prenylaurone (3)) was performed in one step reactions from xanthohumol (1)—major prenylated chalcone naturally occurring in hops. Obtained flavonoids (2–3) and xanthohumol (1) we...

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Detalles Bibliográficos
Autores principales: Tronina, Tomasz, Strugała, Paulina, Popłoński, Jarosław, Włoch, Aleksandra, Sordon, Sandra, Bartmańska, Agnieszka, Huszcza, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152009/
https://www.ncbi.nlm.nih.gov/pubmed/28754033
http://dx.doi.org/10.3390/molecules22071230