Cargando…

The Influence of Glycosylation of Natural and Synthetic Prenylated Flavonoids on Binding to Human Serum Albumin and Inhibition of Cyclooxygenases COX-1 and COX-2

The synthesis of different classes of prenylated aglycones (α,β-dihydroxanthohumol (2) and (Z)-6,4’-dihydroxy-4-methoxy-7-prenylaurone (3)) was performed in one step reactions from xanthohumol (1)—major prenylated chalcone naturally occurring in hops. Obtained flavonoids (2–3) and xanthohumol (1) we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tronina, Tomasz, Strugała, Paulina, Popłoński, Jarosław, Włoch, Aleksandra, Sordon, Sandra, Bartmańska, Agnieszka, Huszcza, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152009/ https://www.ncbi.nlm.nih.gov/pubmed/28754033 http://dx.doi.org/10.3390/molecules22071230

Ejemplares similares

Prenylated Flavonoids with Selective Toxicity against Human Cancers
por: Tronina, Tomasz, et al.
Publicado: (2023)

Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization
por: Popłoński, Jarosław, et al.
Publicado: (2018)

Antimicrobial Properties of Spent Hops Extracts, Flavonoids Isolated Therefrom, and Their Derivatives
por: Bartmańska, Agnieszka, et al.
Publicado: (2018)

Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A
por: Sordon, Sandra, et al.
Publicado: (2017)

Simple and Rapid Method for Wogonin Preparation and Its Biotransformation
por: Tronina, Tomasz, et al.
Publicado: (2021)

Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids
por: Bartmańska, Agnieszka, et al.
Publicado: (2018)

Flavonoids as Phytoestrogenic Components of Hops and Beer
por: Tronina, Tomasz, et al.
Publicado: (2020)

Evaluation of double expression system for co-expression and co-immobilization of flavonoid glucosylation cascade
por: Matera, Agata, et al.
Publicado: (2022)

Novel flavonoid C-8 hydroxylase from Rhodotorula glutinis: identification, characterization and substrate scope
por: Dulak, Kinga, et al.
Publicado: (2022)

Structure–Antioxidant–Antiproliferative Activity Relationships of Natural C7 and C7–C8 Hydroxylated Flavones and Flavanones
por: Sordon, Sandra, et al.
Publicado: (2019)

Bioactivity In Vitro of Quercetin Glycoside Obtained in Beauveria bassiana Culture and Its Interaction with Liposome Membranes
por: Strugała, Paulina, et al.
Publicado: (2017)

Cyclooxygenase (COX) Inhibitors and the Newborn Kidney
por: Smith, Francine G., et al.
Publicado: (2012)

Colorectal Carcinoma, Cyclooxygenases, and COX Inhibitors
por: Ganduri, Vinutna, et al.
Publicado: (2022)

Antiplatelet Effect and Selective Binding to Cyclooxygenase (COX) by Molecular Docking Analysis of Flavonoids and Lignans
por: Wu, Chien-Ming, et al.
Publicado: (2007)

Chiral Derivatives of Xanthones: Investigation of the Effect of Enantioselectivity on Inhibition of Cyclooxygenases (COX-1 and COX-2) and Binding Interaction with Human Serum Albumin
por: Fernandes, Carla, et al.
Publicado: (2017)

The Effect of Xanthohumol Derivatives on Apoptosis Induction in Canine Lymphoma and Leukemia Cell Lines
por: Grudzień, Małgorzata, et al.
Publicado: (2023)

Expression of cyclooxygenase-2 (COX-2) in pituitary tumours
por: Sokołowski, Grzegorz, et al.
Publicado: (2012)

Improved Oxidation of Naringenin to Carthamidin and Isocarthamidin by Rhodotorula marina
por: Madej, Anna, et al.
Publicado: (2014)

Cyclooxygenase in normal human tissues – is COX-1 really a constitutive isoform, and COX-2 an inducible isoform?
por: Zidar, Nina, et al.
Publicado: (2009)

Cyclooxygenase-1 (COX-1) and COX-1 Inhibitors in Cancer: A Review of Oncology and Medicinal Chemistry Literature
por: Pannunzio, Alessandra, et al.
Publicado: (2018)

Three-dimensional structure of human cyclooxygenase (hCOX)-1
por: Miciaccia, Morena, et al.
Publicado: (2021)

Pancreatic Stellate Cells (PSCs) express Cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs
por: Yoshida, Seiya, et al.
Publicado: (2005)

Binding Energy Calculation of Patchouli Alcohol Isomer Cyclooxygenase Complexes Suggested as COX-1/COX-2 Selective Inhibitor
por: Raharjo, Sentot Joko, et al.
Publicado: (2014)

Flavonoids: Antiplatelet Effect as Inhibitors of COX-1
por: Zaragozá, Cristina, et al.
Publicado: (2022)

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney
por: Pelligand, L., et al.
Publicado: (2015)

Nucleobindin Co-Localizes and Associates with Cyclooxygenase (COX)-2 in Human Neutrophils
por: Leclerc, Patrick, et al.
Publicado: (2008)

Analysis of the Activity and Expression of Cyclooxygenases COX1 and COX2 in THP-1 Monocytes and Macrophages Cultured with Biodentine(TM) Silicate Cement
por: Barczak, Katarzyna, et al.
Publicado: (2020)

Cox-2: Where are we in 2003? - The role of cyclooxygenase-2 in bone repair
por: Einhorn, Thomas A
Publicado: (2003)

Reduction in cancer risk by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors
por: Harris, Randall E, et al.
Publicado: (2012)

Cyclooxygenase-2 (COX-2) inhibitors: future therapeutic strategies for epilepsy management
por: Rawat, Chitra, et al.
Publicado: (2019)

Bioactivity of dihydropyrimidinone derivatives as inhibitors of cyclooxygenase-2 (COX-2): an in silico approach
por: Haq, Kautsar Ul, et al.
Publicado: (2023)

Flavocoxid Inhibits Phospholipase A2, Peroxidase Moieties of the Cyclooxygenases (COX), and 5-Lipoxygenase, Modifies COX-2 Gene Expression, and Acts as an Antioxidant
por: Burnett, Bruce P., et al.
Publicado: (2011)

Interaction of 4′-methylflavonoids with biological membranes, liposomes, and human albumin
por: Włoch, Aleksandra, et al.
Publicado: (2021)

Cyclooxygenase-2 (COX-2) as a Target of Anticancer Agents: A Review of Novel Synthesized Scaffolds Having Anticancer and COX-2 Inhibitory Potentialities
por: Mohsin, Noor ul Amin, et al.
Publicado: (2022)

Reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors
por: Harris, Randall E, et al.
Publicado: (2006)

Acyl chain-dependent effect of lysophosphatidylcholine on cyclooxygenase (COX)-2 expression in endothelial cells
por: Brkić, Lada, et al.
Publicado: (2012)

Regional Differences in the Neuronal Expression of Cyclooxygenase-2 (COX-2) in the Newborn Pig Brain
por: Oláh, Orsolya, et al.
Publicado: (2012)

Reversible Suppression of Cyclooxygenase 2 (COX-2) Expression In Vivo by Inducible RNA Interference
por: Zaiss, Anne K., et al.
Publicado: (2014)

Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice
por: Kim, Joohwee, et al.
Publicado: (2016)

The Molecular Basis for Dual Fatty Acid Amide Hydrolase (FAAH)/Cyclooxygenase (COX) Inhibition
por: Palermo, Giulia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_go3jsofh16nq0glumvmogmkv6t