Cell-Free Production of Pentacyclic Triterpenoid Compound Betulinic Acid from Betulin by the Engineered Saccharomyces cerevisiae

Betulinic acid is a product of plant secondary metabolism which has shown various bioactivities. Several CYP716A subfamily genes were recently characterized encoding multifunctional oxidases capable of C-28 oxidation. CYP716A12 was identified as betulin C-28 oxidase, capable of modifying betulin. Th...

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Detalles Bibliográficos
Autores principales: Wu, Jianan, Niu, Yongwu, Bakur, Abdelmoneim, Li, Hao, Chen, Qihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152010/
https://www.ncbi.nlm.nih.gov/pubmed/28653998
http://dx.doi.org/10.3390/molecules22071075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152010/
https://www.ncbi.nlm.nih.gov/pubmed/28653998
http://dx.doi.org/10.3390/molecules22071075

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