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On the Reaction of Carbonyl Diphosphonic Acid with Hydroxylamine and O-alkylhydroxylamines: Unexpected Degradation of P-C-P Bridge

Derivatives of methylenediphosphonic acid possess wide spectra of biological activities and are used in enzymology as research tools as well as in practical medicine. Carbonyl diphosphonic acid is a promising starting building block for synthesis of functionally substituted methylenediphosphonates....

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Detalles Bibliográficos
Autores principales: Khomich, Olga A., Yanvarev, Dmitry V., Novikov, Roman A., Kornev, Alexey B., Puljulla, Elina, Vepsäläinen, Jouko, Khomutov, Alex R., Kochetkov, Sergey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152022/
https://www.ncbi.nlm.nih.gov/pubmed/28644411
http://dx.doi.org/10.3390/molecules22071040