Inhibitors of the Detoxifying Enzyme of the Phytoalexin Brassinin Based on Quinoline and Isoquinoline Scaffolds

The detoxification of the phytoalexin brassinin to indole-3-carboxaldehyde and S-methyl dithiocarbamate is catalyzed by brassinin oxidase (BOLm), an inducible fungal enzyme produced by the plant pathogen Leptosphaeria maculans. Twenty-six substituted quinolines and isoquinolines are synthesized and...

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Detalles Bibliográficos
Autores principales: Pedras, M. Soledade C., Abdoli, Abbas, Sarma-Mamillapalle, Vijay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152025/
https://www.ncbi.nlm.nih.gov/pubmed/28805743
http://dx.doi.org/10.3390/molecules22081345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152025/
https://www.ncbi.nlm.nih.gov/pubmed/28805743
http://dx.doi.org/10.3390/molecules22081345

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