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Development of a UPLC-MS/MS Method for Simultaneous Determination of Six Flavonoids in Rat Plasma after Administration of Maydis stigma Extract and Its Application to a Comparative Pharmacokinetic Study in Normal and Diabetic Rats

Maydis stigma is an important medicine herb used in many parts of the world for treatment of diabetes mellitus, which main bioactive ingredients are flavonoids. This paper describes for the first time a study on the comparative pharmacokinetics of six active flavonoid ingredients of Maydis stigma in...

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Detalles Bibliográficos
Autores principales: Wei, Bin-Bin, Chen, Zai-Xing, Liu, Ming-Yan, Wei, Min-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152039/
https://www.ncbi.nlm.nih.gov/pubmed/28758910
http://dx.doi.org/10.3390/molecules22081267