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Engineering of a Potent Recombinant Lectin-Toxin Fusion Protein to Eliminate Human Pluripotent Stem Cells

The use of human pluripotent stem cells (hPSCs) such as human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) in regenerative medicine is hindered by their tumorigenic potential. Previously, we developed a recombinant lectin-toxin fusion protein of the hPSC-specific le...

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Detalles Bibliográficos
Autores principales: Tateno, Hiroaki, Minoshima, Fumi, Saito, Sayoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152053/
https://www.ncbi.nlm.nih.gov/pubmed/28698527
http://dx.doi.org/10.3390/molecules22071151