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Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy

Antibody-drug conjugates (ADCs) are a class of highly potent biopharmaceutical drugs generated by conjugating cytotoxic drugs with specific monoclonal antibodies through appropriate linkers. Specific antibodies used to guide potent warheads to tumor tissues can effectively reduce undesired side effe...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Lin, Zongtao, Arnst, Kinsie E., Miller, Duane D., Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152078/
https://www.ncbi.nlm.nih.gov/pubmed/28763044
http://dx.doi.org/10.3390/molecules22081281