Site-Specific PEGylated Adeno-Associated Viruses with Increased Serum Stability and Reduced Immunogenicity

Adeno-associated virus (AAV) is one of the most extensively studied and utilized viral vectors in clinical gene transfer research. However, the serum instability and immunogenicity of AAV vectors significantly limit their application. Here, we endeavored to overcome these limitations by developing a...

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Detalles Bibliográficos
Autores principales: Yao, Tianzhuo, Zhou, Xueying, Zhang, Chuanling, Yu, Xiaojuan, Tian, Zhenyu, Zhang, Lihe, Zhou, Demin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152081/
https://www.ncbi.nlm.nih.gov/pubmed/28696391
http://dx.doi.org/10.3390/molecules22071155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152081/
https://www.ncbi.nlm.nih.gov/pubmed/28696391
http://dx.doi.org/10.3390/molecules22071155

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