Proteomics Analysis Reveals an Important Role for the PPAR Signaling Pathway in DBDCT-Induced Hepatotoxicity Mechanisms

A patented organotin di-n-butyl-di-(4-chlorobenzohydroxamato)tin (DBDCT) with high a antitumor activity was designed, however, its antitumor and toxic mechanisms have not yet been clearly illustrated. Hepatic proteins of DBDCT-treated rats were identified and analyzed using LC-MS/MS with label-free...

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Detalles Bibliográficos
Autores principales: Li, Yunlan, Liu, Xinxin, Niu, Lin, Li, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152083/
https://www.ncbi.nlm.nih.gov/pubmed/28684700
http://dx.doi.org/10.3390/molecules22071113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152083/
https://www.ncbi.nlm.nih.gov/pubmed/28684700
http://dx.doi.org/10.3390/molecules22071113

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