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Mechanism Exploration of Arylpiperazine Derivatives Targeting the 5-HT(2A) Receptor by In Silico Methods

As a G-protein coupled receptor, the 5-hydroxytryptamine 2A (5-HT(2A)) receptor is known for its critical role in the cognitive, behavioural and physiological functions, and thus is a primary molecular target to treat psychiatric diseases, including especially depression. With purpose to explore the...

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Detalles Bibliográficos
Autores principales: Lin, Feng, Li, Feng, Wang, Chao, Wang, Jinghui, Yang, Yinfeng, Yang, Ling, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152085/
https://www.ncbi.nlm.nih.gov/pubmed/28672848
http://dx.doi.org/10.3390/molecules22071064