Extended Physicochemical Characterization of the Synthetic Anticoagulant Pentasaccharide Fondaparinux Sodium by Quantitative NMR and Single Crystal X-ray Analysis

Fondaparinux sodium is a synthetic pentasaccharide representing the high affinity antithrombin III binding site in heparin. It is the active pharmaceutical ingredient of the anticoagulant drug Arixtra(®). The single crystal X-ray structure of Fondaparinux sodium is reported, unequivocally confirming...

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Detalles Bibliográficos
Autores principales: de Wildt, William, Kooijman, Huub, Funke, Carel, Üstün, Bülent, Leika, Afranina, Lunenburg, Maarten, Kaspersen, Frans, Kellenbach, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152090/
https://www.ncbi.nlm.nih.gov/pubmed/28817073
http://dx.doi.org/10.3390/molecules22081362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152090/
https://www.ncbi.nlm.nih.gov/pubmed/28817073
http://dx.doi.org/10.3390/molecules22081362

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