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Extended Physicochemical Characterization of the Synthetic Anticoagulant Pentasaccharide Fondaparinux Sodium by Quantitative NMR and Single Crystal X-ray Analysis

Fondaparinux sodium is a synthetic pentasaccharide representing the high affinity antithrombin III binding site in heparin. It is the active pharmaceutical ingredient of the anticoagulant drug Arixtra(®). The single crystal X-ray structure of Fondaparinux sodium is reported, unequivocally confirming...

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Detalles Bibliográficos
Autores principales:	de Wildt, William, Kooijman, Huub, Funke, Carel, Üstün, Bülent, Leika, Afranina, Lunenburg, Maarten, Kaspersen, Frans, Kellenbach, Edwin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152090/ https://www.ncbi.nlm.nih.gov/pubmed/28817073 http://dx.doi.org/10.3390/molecules22081362

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