Sulfonamide-Linked Ciprofloxacin, Sulfadiazine and Amantadine Derivatives as a Novel Class of Inhibitors of Jack Bean Urease; Synthesis, Kinetic Mechanism and Molecular Docking

Sulfonamide derivatives serve as an important building blocks in the drug design discovery and development (4D) process. Ciprofloxacin-, sulfadiazine- and amantadine-based sulfonamides were synthesized as potent inhibitors of jack bean urease and free radical scavengers. Molecular diversity was expl...

Descripción completa

Detalles Bibliográficos
Autores principales: Channar, Pervaiz Ali, Saeed, Aamer, Albericio, Fernando, Larik, Fayaz Ali, Abbas, Qamar, Hassan, Mubashir, Raza, Hussain, Seo, Sung-Yum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152116/
https://www.ncbi.nlm.nih.gov/pubmed/28813027
http://dx.doi.org/10.3390/molecules22081352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152116/
https://www.ncbi.nlm.nih.gov/pubmed/28813027
http://dx.doi.org/10.3390/molecules22081352

Ejemplares similares