Facile Synthesis of Novel Coumarin Derivatives, Antimicrobial Analysis, Enzyme Assay, Docking Study, ADMET Prediction and Toxicity Study

The work reports the synthesis under solvent-free condition using the ionic liquid [Et(3)NH][HSO(4)] as a catalyst of fifteen novel 3-((dicyclohexylamino)(substituted phenyl/heteryl)-methyl)-4-hydroxy-2H-chromen-2-onederivatives 4a–o as potential antimicrobial agents. The structures of the synthesiz...

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Detalles Bibliográficos
Autores principales: Tiwari, Shailee V., Seijas, Julio A., Vazquez-Tato, Maria Pilar, Sarkate, Aniket P., Karnik, Kshipra S., Nikalje, Anna Pratima G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152127/
https://www.ncbi.nlm.nih.gov/pubmed/28703783
http://dx.doi.org/10.3390/molecules22071172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152127/
https://www.ncbi.nlm.nih.gov/pubmed/28703783
http://dx.doi.org/10.3390/molecules22071172

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