The Role of Solvent-Accessible Leu-208 of Cold-Active Pseudomonas fluorescens Strain AMS8 Lipase in Interfacial Activation, Substrate Accessibility and Low-Molecular Weight Esterification in the Presence of Toluene

The alkaline cold-active lipase from Pseudomonas fluorescens AMS8 undergoes major structural changes when reacted with hydrophobic organic solvents. In toluene, the AMS8 lipase catalytic region is exposed by the moving hydrophobic lid 2 (Glu-148 to Gly-167). Solvent-accessible surface area analysis...

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Detalles Bibliográficos
Autores principales: Yaacob, Norhayati, Ahmad Kamarudin, Nor Hafizah, Leow, Adam Thean Chor, Salleh, Abu Bakar, Raja Abd Rahman, Raja Noor Zaliha, Mohamad Ali, Mohd Shukuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152135/
https://www.ncbi.nlm.nih.gov/pubmed/28805665
http://dx.doi.org/10.3390/molecules22081312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152135/
https://www.ncbi.nlm.nih.gov/pubmed/28805665
http://dx.doi.org/10.3390/molecules22081312

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