Design, Synthesis and Evaluation of Hesperetin Derivatives as Potential Multifunctional Anti-Alzheimer Agents

In this study we designed and synthesized a series of new hesperetin derivatives on the basis of the structural characteristics of acetylcholinesterase (AChE) dual-site inhibitors. The activity of the novel derivatives was also evaluated. Results showed that the synthesized hesperetin derivatives di...

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Detalles Bibliográficos
Autores principales: Li, Bo, Huang, Ai-Ling, Zhang, Yi-Long, Li, Zeng, Ding, Hai-Wen, Huang, Cheng, Meng, Xiao-Ming, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152180/
https://www.ncbi.nlm.nih.gov/pubmed/28672874
http://dx.doi.org/10.3390/molecules22071067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152180/
https://www.ncbi.nlm.nih.gov/pubmed/28672874
http://dx.doi.org/10.3390/molecules22071067

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