Rapid Mechanistic Evaluation and Parameter Estimation of Putative Inhibitors in a Single-Step Progress-Curve Analysis: The Case of Horse Butyrylcholinesterase

Highly efficient and rapid lead compound evaluation for estimation of inhibition parameters and type of inhibition is proposed. This is based on a single progress-curve measurement in the presence of each candidate compound, followed by the simultaneous analysis of all of these curves using the ENZO...

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Detalles Bibliográficos
Autor principal: Stojan, Jure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152194/
https://www.ncbi.nlm.nih.gov/pubmed/28933751
http://dx.doi.org/10.3390/molecules22081248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152194/
https://www.ncbi.nlm.nih.gov/pubmed/28933751
http://dx.doi.org/10.3390/molecules22081248

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