L1210 Cells Overexpressing ABCB1 Drug Transporters Are Resistant to Inhibitors of the N- and O-glycosylation of Proteins

Overexpression of P-glycoprotein (P-gp, drug transporter) in neoplastic cells is the most frequently observed molecular cause of multidrug resistance. Here, we show that the overexpression of P-gp in L1210 cells leads to resistance to tunicamycin and benzyl 2-acetamido-2-deoxy-α-d-galactopyranoside...

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Detalles Bibliográficos
Autores principales: Pavlikova, Lucia, Seres, Mario, Hano, Milan, Bohacova, Viera, Sevcikova, Ivana, Kyca, Tomas, Breier, Albert, Sulova, Zdena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152248/
https://www.ncbi.nlm.nih.gov/pubmed/28671633
http://dx.doi.org/10.3390/molecules22071104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152248/
https://www.ncbi.nlm.nih.gov/pubmed/28671633
http://dx.doi.org/10.3390/molecules22071104

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