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Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date

The cytochrome P450 (CYP) family 1A enzymes, CYP1A1 and CYP1A2, are two of the most important enzymes implicated in the metabolism of endogenous and exogenous compounds through oxidation. These enzymes are also known to metabolize environmental procarcinogens into carcinogenic species, leading to th...

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Detalles Bibliográficos
Autores principales: Sridhar, Jayalakshmi, Goyal, Navneet, Liu, Jiawang, Foroozesh, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152251/
https://www.ncbi.nlm.nih.gov/pubmed/28698457
http://dx.doi.org/10.3390/molecules22071143