Synthesis and In Vitro Antimycobacterial and Antibacterial Activity of 8-OMe Ciprofloxacin-Hydrozone/Azole Hybrids

A series of novel 8-OMe ciprofloxacin (CPFX)-hydrazone/azole hybrids were designed, synthesized, and evaluated for their in vitro biological activities. Our results reveal that all of the hydrozone-containing hybrids (except for 7) show potency against Mycobacterium tuberculosis (MTB) H(37)Rv (minim...

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Detalles Bibliográficos
Autores principales: Xu, Zhi, Zhang, Shu, Feng, Lian-Shun, Li, Xiao-Ning, Huang, Guo-Cheng, Chai, Yun, Lv, Zao-Sheng, Guo, Hui-Yuan, Liu, Ming-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152256/
https://www.ncbi.nlm.nih.gov/pubmed/28703766
http://dx.doi.org/10.3390/molecules22071171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152256/
https://www.ncbi.nlm.nih.gov/pubmed/28703766
http://dx.doi.org/10.3390/molecules22071171

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