Synthesis and Biological Evaluation of Ginsenoside Compound K Derivatives as a Novel Class of LXRα Activator

Compound K is one of the active metabolites of Panaxnotoginseng saponins, which could attenuate the formation of atherosclerosis in mice modelsvia activating LXRα. We synthesized and evaluated a series of ginsenoside compound K derivatives modified with short chain fatty acids. All of the structures...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Liu, Hongmei, Zhang, Yingxian, Li, Jin, Wang, Chenping, Zhou, Li, Jia, Yi, Li, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152260/
https://www.ncbi.nlm.nih.gov/pubmed/28737726
http://dx.doi.org/10.3390/molecules22071232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152260/
https://www.ncbi.nlm.nih.gov/pubmed/28737726
http://dx.doi.org/10.3390/molecules22071232

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