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Synthesis and Biological Evaluation of Ginsenoside Compound K Derivatives as a Novel Class of LXRα Activator
Compound K is one of the active metabolites of Panaxnotoginseng saponins, which could attenuate the formation of atherosclerosis in mice modelsvia activating LXRα. We synthesized and evaluated a series of ginsenoside compound K derivatives modified with short chain fatty acids. All of the structures...
Autores principales: | Huang, Yan, Liu, Hongmei, Zhang, Yingxian, Li, Jin, Wang, Chenping, Zhou, Li, Jia, Yi, Li, Xiaohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152260/ https://www.ncbi.nlm.nih.gov/pubmed/28737726 http://dx.doi.org/10.3390/molecules22071232 |
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