Design, Synthesis, and Biological Activity of New Triazole and Nitro-Triazole Derivatives as Antifungal Agents

In this study two series of fluconazole derivatives bearing nitrotriazole (series A) or piperazine ethanol (series B) side chain were designed and synthesized and then docked in the active site of lanosterol 14α-demethylase enzyme (1EA1) using the Autodock 4.2 program (The scripps research institute...

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Detalles Bibliográficos
Autores principales: Sadeghpour, Hossein, Khabnadideh, Soghra, Zomorodian, Kamiar, Pakshir, Keyvan, Hoseinpour, Khadijeh, Javid, Nabiollah, Faghih-Mirzaei, Ehsan, Rezaei, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152269/
https://www.ncbi.nlm.nih.gov/pubmed/28698522
http://dx.doi.org/10.3390/molecules22071150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152269/
https://www.ncbi.nlm.nih.gov/pubmed/28698522
http://dx.doi.org/10.3390/molecules22071150

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