Cargando…

Design, Synthesis, and Biological Activity of New Triazole and Nitro-Triazole Derivatives as Antifungal Agents

In this study two series of fluconazole derivatives bearing nitrotriazole (series A) or piperazine ethanol (series B) side chain were designed and synthesized and then docked in the active site of lanosterol 14α-demethylase enzyme (1EA1) using the Autodock 4.2 program (The scripps research institute...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sadeghpour, Hossein, Khabnadideh, Soghra, Zomorodian, Kamiar, Pakshir, Keyvan, Hoseinpour, Khadijeh, Javid, Nabiollah, Faghih-Mirzaei, Ehsan, Rezaei, Zahra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152269/ https://www.ncbi.nlm.nih.gov/pubmed/28698522 http://dx.doi.org/10.3390/molecules22071150

Ejemplares similares

Design, Synthesis, and Antifungal Activity of New α-Aminophosphonates
por: Rezaei, Zahra, et al.
Publicado: (2011)

Design, synthesis and evaluation of novel 1,2,4-triazole derivatives as promising anticancer agents
por: Emami, Leila, et al.
Publicado: (2022)

Binding mode of triazole derivatives as aromatase inhibitors based on docking, protein ligand interaction fingerprinting, and molecular dynamics simulation studies
por: Mojaddami, Ayyub, et al.
Publicado: (2017)

Nano-SnCl(4).SiO(2), an efficient catalyst for synthesis of benzimidazole drivatives as antifungal and cytotoxic agents
por: Zamani, Leila, et al.
Publicado: (2019)

Synthesis of some novel dibromo-2-arylquinazolinone derivatives as cytotoxic agents
por: Faghih, Zeinab, et al.
Publicado: (2019)

Synthesis and antifungal activity of benzimidazole, benzotriazole and aminothiazole derivatives
por: Khabnadideh, S., et al.
Publicado: (2012)

Novel 1, 2, 4-Triazoles as Antifungal Agents
por: Kazeminejad, Zahra, et al.
Publicado: (2022)

Molecular characterization and antifungal activity against non-dermatophyte molds causing onychomycosis
por: Pakshir, Keyvan, et al.
Publicado: (2021)

Docking, Synthesis and Evaluation of the Antifungal Activity of Pyrimido [4,5-b]quinolins
por: Araghi, Reza, et al.
Publicado: (2020)

Chemical Composition, Antifungal and Antibiofilm Activities of the Essential Oil of Mentha piperita L.
por: Saharkhiz, Mohammad Jamal, et al.
Publicado: (2012)

Design, Synthesis, Biological Evaluation and Molecular Modeling Study of Novel Indolizine-1-Carbonitrile Derivatives as Potential Anti-Microbial Agents
por: Faghih-Mirzaei, Ehsan, et al.
Publicado: (2018)

Chemical composition and antifungal activities of aromatic water of Zataria multiflora Boiss.
por: Arabi Monfared, Ali, et al.
Publicado: (2021)

Chemical compositions and antifungal activities of Satureja macrosiphon against Candida and Aspergillus species
por: Motamedi, Marjan, et al.
Publicado: (2019)

Evaluation of CAMP-Like Effect, Biofilm Formation, and Discrimination of Candida africana from Vaginal Candida albicans Species
por: Pakshir, Keyvan, et al.
Publicado: (2017)

Comparative Analysis of Virulence Factors of Homozygous and Heterozygous Strains of Candida albicans Vaginal Isolates
por: Nouraei, Hasti, et al.
Publicado: (2020)

Chemical Composition and Antimicrobial Activities of the Essential Oil From Salvia mirzayanii Leaves
por: Zomorodian, Kamiar, et al.
Publicado: (2017)

Evaluation of fungal contamination and ochratoxin A detection in different types of coffee by HPLC‐based method
por: Pakshir, Keyvan, et al.
Publicado: (2021)

Evaluation of biofilm formation in the homozygous and heterozygous strains of vaginal Candida albicans isolates
por: Pakshir, Keyvan, et al.
Publicado: (2019)

COVID‐19‐associated facial cutaneous mucormycosis superinfection: A potentially life‐threatening disease
por: Zareshahrabadi, Zahra, et al.
Publicado: (2022)

Prevalence of superficial‐cutaneous fungal infections in Shiraz, Iran: A five‐year retrospective study (2015–2019)
por: Khodadadi, Hossein, et al.
Publicado: (2021)

Advances in synthetic approach to and antifungal activity of triazoles
por: Shalini, Kumari, et al.
Publicado: (2011)

Evaluation of Exoenzyme Activities, Biofilm Formation, and Co-hemolytic Effect in Clinical Isolates of Candida parapsilosis Species Complex
por: Pakshir, Keyvan, et al.
Publicado: (2018)

Phenotypes characterization and ABC genotypes distribution of clinical Candida albicans isolates
por: Mahmoodi, Mozhgan, et al.
Publicado: (2023)

Evaluation of building washing machines as an extreme environment for potentially pathogenic fungi
por: Zareshahrabadi, Zahra, et al.
Publicado: (2023)

Biotransformation of acetoin to 2,3-butanediol: Assessment of plant and microbial biocatalysts
por: Javidnia, Katayoun, et al.
Publicado: (2016)

Quinazoline analogues as cytotoxic agents; QSAR, docking, and in silico studies
por: Emami, Leila, et al.
Publicado: (2021)

In Vitro Susceptibility and Trailing Growth Effect of Clinical Isolates of Candida Species to Azole Drugs
por: Zomorodian, Kamiar, et al.
Publicado: (2016)

A 3-nitro triazole as a hypoxic cell sensitizer.
por: Astor, M. B., et al.
Publicado: (1983)

3-Nitro-1H-1,2,4-triazole
por: Hemamalini, Madhukar, et al.
Publicado: (2010)

The Cutaneous Bacterial Microflora of the Bodybuilders Using Anabolic-Androgenic Steroids
por: Zomorodian, Kamiar, et al.
Publicado: (2014)

Isolation and Molecular Identification of Keratinophilic Fungi from Public Parks Soil in Shiraz, Iran
por: Pakshir, Keyvan, et al.
Publicado: (2013)

Synthesis and Evaluation of Baylis-Hillman Reaction Derived Imidazole and Triazole Cinnamates as Antifungal Agents
por: Nelson, Grady L., et al.
Publicado: (2018)

Use of modeling and simulation to predict the influence of triazole antifungal agents on the pharmacokinetics of zanubrutinib and acalabrutinib
por: Chen, Lu, et al.
Publicado: (2022)

Determination of Antifungal Susceptibility Patterns Among the Clinical Isolates of Candida Species
por: Zomorodian, Kamiar, et al.
Publicado: (2011)

Synthesis, biological evaluation, and computational studies of some novel quinazoline derivatives as anticancer agents
por: Emami, Leila, et al.
Publicado: (2022)

Coumarin Triazoles as Potential Antimicrobial Agents
por: Patil, Siddappa A., et al.
Publicado: (2023)

Antifungal synergy of a topical triazole, PC945, with a systemic triazole against respiratory Aspergillus fumigatus infection
por: Colley, Thomas, et al.
Publicado: (2019)

Design, synthesis, computational study and cytotoxic evaluation of some new quinazoline derivatives containing pyrimidine moiety
por: Zare, Somayeh, et al.
Publicado: (2023)

Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent
por: Cass, Lindsey, et al.
Publicado: (2020)

Pharmacovigilance of triazole antifungal agents: Analysis of the FDA adverse event reporting system (FAERS) database
por: Zhou, Jianxing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t9sh05emjvgu2tcl512phfq5rk