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Effects of K11R and G31P Mutations on the Structure and Biological Activities of CXCL8: Solution Structure of Human CXCL8((3-72))K11R/G31P

The ELR-CXC chemokines are important to neutrophil inflammation in many acute and chronic diseases. Among them, CXCL8 (interleukin-8, IL-8), the expression levels of which are elevated in many inflammatory diseases, binds to both the CXCR1 and CXCR2 receptors with high affinity. Recently, an analogu...

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Detalles Bibliográficos
Autores principales: Cheng, Hsi-Tsung, Yu, Hui-Yuan, Gordon, John R., Li, Fang, Cheng, Jya-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152285/
https://www.ncbi.nlm.nih.gov/pubmed/28754019
http://dx.doi.org/10.3390/molecules22071229