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Crystal Structure Analysis of the First Discovered Stability-Enhanced Solid State of Tenofovir Disoproxil Free Base Using Single Crystal X-ray Diffraction

Tenofovir disoproxil (TD), an anti-virus drug, is currently marketed under its most stable form, Form-I of Tenofovir disoproxil fumarate (TDF). However, studies regarding the properties of TD free base crystal as a promising drug as well as its crystal structure have not yet been reported. This assu...

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Detalles Bibliográficos
Autores principales: An, Ji-Hun, Kiyonga, Alice Nguvoko, Yoon, Woojin, Ryu, Hyung Chul, Kim, Jae-Sun, Kang, Chaeri, Park, Minho, Yun, Hoseop, Jung, Kiwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152289/
https://www.ncbi.nlm.nih.gov/pubmed/28708115
http://dx.doi.org/10.3390/molecules22071182