Molecular Dynamics Simulations of the Host Defense Peptide Temporin L and Its Q3K Derivative: An Atomic Level View from Aggregation in Water to Bilayer Perturbation

Temporin L (TempL) is a 13 residue Host Defense Peptide (HDP) isolated from the skin of frogs. It has a strong affinity for lipopolysaccharides (LPS), which is related to its high activity against Gram-negative bacteria and also to its strong tendency to neutralize the pro-inflammatory response caus...

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Detalles Bibliográficos
Autores principales: Farrotti, Andrea, Conflitti, Paolo, Srivastava, Saurabh, Ghosh, Jimut Kanti, Palleschi, Antonio, Stella, Lorenzo, Bocchinfuso, Gianfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152314/
https://www.ncbi.nlm.nih.gov/pubmed/28737669
http://dx.doi.org/10.3390/molecules22071235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152314/
https://www.ncbi.nlm.nih.gov/pubmed/28737669
http://dx.doi.org/10.3390/molecules22071235

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