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Warfarin and Flavonoids Do Not Share the Same Binding Region in Binding to the IIA Subdomain of Human Serum Albumin

Human serum albumin (HSA) binds a variety of xenobiotics, including flavonoids and warfarin. The binding of another ligand to the IIA binding site on HSA can cause warfarin displacement and potentially the elevation of its free concentration in blood. Studies dealing with flavonoid-induced warfarin...

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Detalles Bibliográficos
Autores principales: Rimac, Hrvoje, Dufour, Claire, Debeljak, Željko, Zorc, Branka, Bojić, Mirza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152318/
https://www.ncbi.nlm.nih.gov/pubmed/28696372
http://dx.doi.org/10.3390/molecules22071153