High-Resolution Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Vietnamese Plants

Protein tyrosine phosphatase 1B (PTP1B) plays a key role as a negative regulator in insulin signal transduction by deactivating the insulin receptor. Thus, PTP1B inhibition has emerged as a potential therapeutic strategy for curing insulin resistance. In this study, 40 extracts from 18 different pla...

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Detalles Bibliográficos
Autores principales: Trinh, Binh Thi Dieu, Jäger, Anna K., Staerk, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152321/
https://www.ncbi.nlm.nih.gov/pubmed/28726759
http://dx.doi.org/10.3390/molecules22071228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152321/
https://www.ncbi.nlm.nih.gov/pubmed/28726759
http://dx.doi.org/10.3390/molecules22071228

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