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Synthesis and Evaluation of New Oxadiazole, Thiadiazole, and Triazole Derivatives as Potential Anticancer Agents Targeting MMP-9

Matrix metalloproteinases (MMPs) are important proteases involved in tumor progression including angiogenesis, tissue invasion, and migration. Therefore, MMPs have been reported as potential diagnostic and prognostic biomarkers in many types of cancer. New oxadiazole, thiadiazole, and triazole deriv...

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Detalles Bibliográficos
Autores principales: Özdemir, Ahmet, Sever, Belgin, Altıntop, Mehlika Dilek, Temel, Halide Edip, Atlı, Özlem, Baysal, Merve, Demirci, Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152322/
https://www.ncbi.nlm.nih.gov/pubmed/28677624
http://dx.doi.org/10.3390/molecules22071109