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Immunogenicity of propagation-restricted vesicular stomatitis virus encoding Ebola virus glycoprotein in guinea pigs

Vesicular stomatitis virus (VSV) expressing the Ebola virus (EBOV) glycoprotein (GP) in place of the VSV glycoprotein G (VSV/EBOV-GP) is a promising EBOV vaccine candidate which has already entered clinical phase 3 studies. Although this chimeric virus was tolerated overall by volunteers, it still c...

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Detalles Bibliográficos
Autores principales: Locher, Samira, Schweneker, Marc, Hausmann, Jürgen, Zimmer, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152369/
https://www.ncbi.nlm.nih.gov/pubmed/29869979
http://dx.doi.org/10.1099/jgv.0.001085