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Artesunate Activates the Intrinsic Apoptosis of HCT116 Cells through the Suppression of Fatty Acid Synthesis and the NF-κB Pathway

The artemisinin compounds, which are well-known for their potent therapeutic antimalarial activity, possess in vivo and in vitro antitumor effects. Although the anticancer effect of artemisinin compounds has been extensively reported, the precise mechanisms underlying its cytotoxicity remain under i...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Wong, Yin Kwan, Lim, Teck Kwang, Lim, Wei Hou, Lin, Qingsong, Wang, Jigang, Hua, Zichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152404/
https://www.ncbi.nlm.nih.gov/pubmed/28786914
http://dx.doi.org/10.3390/molecules22081272