A new drug combination significantly reduces kidney tumor progression in kidney mouse model

Tuberous sclerosis complex (TSC) disease is associated with tumors in many organs, particularly angiomyolipoma (AML) in the kidneys. Loss or inactivation of TSC1/2 results in high levels of HIF-α activity and VEGF expression. mTOR inhibitor (rapamycin) and the AMPK activator 5-aminoimidazole-4-carbo...

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Detalles Bibliográficos
Autores principales: Liang, Sitai, Cuellar, Tiffanie, Nowacki, Maciej, Nayak, Bijaya K., Dong, Lily, Li, Boajie, Sharma, Kumar, Habib, Samy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152473/
https://www.ncbi.nlm.nih.gov/pubmed/30250638
http://dx.doi.org/10.18632/oncotarget.26004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152473/
https://www.ncbi.nlm.nih.gov/pubmed/30250638
http://dx.doi.org/10.18632/oncotarget.26004

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