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Synergistic combination of flavopiridol and carfilzomib targets commonly dysregulated pathways in adrenocortical carcinoma and has biomarkers of response

Drug repurposing is an effective approach to identify active drugs with known toxicity profiles for rare cancers such as ACC. The objective of this study was to determine the anticancer activity of combination treatment for ACC from previously identified candidate agents using quantitative high-thro...

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Detalles Bibliográficos
Autores principales: Nilubol, Naris, Boufraqech, Myriem, Zhang, Lisa, Gaskins, Kelli, Shen, Min, Zhang, Ya-Qin, Gara, Sudheer K., Austin, Christopher P., Kebebew, Electron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152480/
https://www.ncbi.nlm.nih.gov/pubmed/30250647
http://dx.doi.org/10.18632/oncotarget.26050