Synthesis and Evaluation of Phenylxanthine Derivatives as Potential Dual A2AR Antagonists/MAO-B Inhibitors for Parkinson’s Disease

The aim of this research was to prove the speculation that phenylxanthine (PX) derivatives possess adenosine A2A receptor (A2AR)-blocking properties and to screening and evaluate these PX derivatives as dual A2AR antagonists/MAO-B inhibitors for Parkinson′s disease. To explore this hypothesis, two s...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xuebao, Han, Chao, Xu, Yong, Wu, Kaiqi, Chen, Shuangya, Hu, Mangsha, Wang, Luyao, Ye, Yun, Ye, Faqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152622/
https://www.ncbi.nlm.nih.gov/pubmed/28629145
http://dx.doi.org/10.3390/molecules22061010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152622/
https://www.ncbi.nlm.nih.gov/pubmed/28629145
http://dx.doi.org/10.3390/molecules22061010

Ejemplares similares