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Levo-Corydalmine Alleviates Neuropathic Cancer Pain Induced by Tumor Compression via the CCL2/CCR2 Pathway

Background: Tumor compression-induced pain (TCIP) is a complex pathological cancer pain. Spinal glial cells play a critical role in maintenance of cancer pain by releasing proinflammatory cytokines and chemokines. In this study, we verified the role of levo-corydalmine (l-CDL) on TCIP. Methods: Spon...

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Detalles Bibliográficos
Autores principales: Hu, Yahui, Kodithuwakku, Nandani Darshika, Zhou, Lin, Li, Chengyuan, Han, Dan, Fang, Weirong, Liu, Jihua, Li, Yunman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152665/
https://www.ncbi.nlm.nih.gov/pubmed/28587280
http://dx.doi.org/10.3390/molecules22060937