Identification of Novel Vacuolin-1 Analogues as Autophagy Inhibitors by Virtual Drug Screening and Chemical Synthesis

Autophagy is a fundamental cellular degradation process which is essential for cell homeostasis, and dysfunctional autophagy has been associated with a variety of human diseases, such as cancer. Several autophagy chemical modulators have been applied in a number of preclinical or clinical trials aga...

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Detalles Bibliográficos
Autores principales: Chen, Chang, Lu, Yingying, Siu, Ho Ming, Guan, Jintao, Zhu, Longchao, Zhang, Shuang, Yue, Jianbo, Zhang, Liangren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152680/
https://www.ncbi.nlm.nih.gov/pubmed/28555021
http://dx.doi.org/10.3390/molecules22060891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152680/
https://www.ncbi.nlm.nih.gov/pubmed/28555021
http://dx.doi.org/10.3390/molecules22060891

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