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Synthesis and Biological Activity Evaluation of Novel Heterocyclic Pleuromutilin Derivatives

A series of pleuromutilin derivatives were synthesized by two synthetic procedures under mild reaction conditions and characterized by Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), and High Resolution Mass Spectrometer (HRMS). Most of the derivatives with heterocyclic groups at the C...

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Detalles Bibliográficos
Autores principales: Yi, Yunpeng, Fu, Yunxing, Dong, Pengcheng, Qin, Wenwen, Liu, Yu, Liang, Jiangping, Shang, Ruofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152684/
https://www.ncbi.nlm.nih.gov/pubmed/28617344
http://dx.doi.org/10.3390/molecules22060996