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Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative

Scutellarin (1) has been widely used to treat acute cerebral infarction in clinic, but poor aqueous solubility decreases its bioavailability. Interestingly, scutellarin (1) could be metabolized into scutellarein (2) in vivo. In this study, a sulfonic group was introduced at position C-8 of scutellar...

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Detalles Bibliográficos
Autores principales: Gu, Ting, Zhong, Yue, Lu, Yu-Ting, Sun, Ying, Dong, Ze-Xi, Wu, Wen-Yu, Shi, Zhi-Hao, Li, Nian-Guang, Xue, Xin, Fang, Fang, Li, He-Min, Tang, Yu-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152701/
https://www.ncbi.nlm.nih.gov/pubmed/28635646
http://dx.doi.org/10.3390/molecules22061028