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Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative
Scutellarin (1) has been widely used to treat acute cerebral infarction in clinic, but poor aqueous solubility decreases its bioavailability. Interestingly, scutellarin (1) could be metabolized into scutellarein (2) in vivo. In this study, a sulfonic group was introduced at position C-8 of scutellar...
Autores principales: | Gu, Ting, Zhong, Yue, Lu, Yu-Ting, Sun, Ying, Dong, Ze-Xi, Wu, Wen-Yu, Shi, Zhi-Hao, Li, Nian-Guang, Xue, Xin, Fang, Fang, Li, He-Min, Tang, Yu-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152701/ https://www.ncbi.nlm.nih.gov/pubmed/28635646 http://dx.doi.org/10.3390/molecules22061028 |
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