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Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer’s Agents: Design, Synthesis and Biological Evaluation

A novel series of 6-chlorotacrine-scutellarin hybrids was designed, synthesized and the biological activity as potential anti-Alzheimer’s agents was assessed. Their inhibitory activity towards human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBChE), antioxidant activity, ability t...

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Detalles Bibliográficos
Autores principales:	Spilovska, Katarina, Korabecny, Jan, Sepsova, Vendula, Jun, Daniel, Hrabinova, Martina, Jost, Petr, Muckova, Lubica, Soukup, Ondrej, Janockova, Jana, Kucera, Tomas, Dolezal, Rafael, Mezeiova, Eva, Kaping, Daniel, Kuca, Kamil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152717/ https://www.ncbi.nlm.nih.gov/pubmed/28621747 http://dx.doi.org/10.3390/molecules22061006

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