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Design and Synthesis of Dendrimers with Facile Surface Group Functionalization, and an Evaluation of Their Bactericidal Efficacy

We report a versatile divergent methodology to construct dendrimers from a tetrafunctional core, utilizing the robust copper(I) catalyzed alkyne-azide cycloaddition (CuAAC, “click”) reaction for both dendrimer synthesis and post-synthesis functionalization. Dendrimers of generations 1–3 with 8–32 pr...

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Detalles Bibliográficos
Autores principales: Ladd, Elizabeth, Sheikhi, Amir, Li, Na, van de Ven, Theo G.M., Kakkar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152728/
https://www.ncbi.nlm.nih.gov/pubmed/28538670
http://dx.doi.org/10.3390/molecules22060868