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In Vitro Antioxidant Activity of Idebenone Derivative-Loaded Solid Lipid Nanoparticles

Idebenone (IDE) has been proposed for the treatment of neurodegenerative diseases involving mitochondria dysfunctions. Unfortunately, to date, IDE therapeutic treatments have not been as successful as expected. To improve IDE efficacy, in this work we describe a two-step approach: (1) synthesis of I...

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Detalles Bibliográficos
Autores principales: Montenegro, Lucia, Modica, Maria N., Salerno, Loredana, Panico, Anna Maria, Crascì, Lucia, Puglisi, Giovanni, Romeo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152785/
https://www.ncbi.nlm.nih.gov/pubmed/28555014
http://dx.doi.org/10.3390/molecules22060887