Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patients

AIMS: IgA nephropathy, the most common primary glomerulonephritis worldwide, is characterized by glomerular deposition of galactose-deficient IgA1 and elevated serum levels of this IgA1 glycoform. Current ELISA methods lack sensitivity to assess galactose deficiency using small amounts of IgA1, whic...

Descripción completa

Detalles Bibliográficos
Autores principales: Reily, Colin, Rizk, Dana V, Julian, Bruce A, Novak, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152805/
https://www.ncbi.nlm.nih.gov/pubmed/30091383
http://dx.doi.org/10.2144/btn-2018-0042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152805/
https://www.ncbi.nlm.nih.gov/pubmed/30091383
http://dx.doi.org/10.2144/btn-2018-0042

Ejemplares similares