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Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patients
AIMS: IgA nephropathy, the most common primary glomerulonephritis worldwide, is characterized by glomerular deposition of galactose-deficient IgA1 and elevated serum levels of this IgA1 glycoform. Current ELISA methods lack sensitivity to assess galactose deficiency using small amounts of IgA1, whic...
Autores principales: | Reily, Colin, Rizk, Dana V, Julian, Bruce A, Novak, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152805/ https://www.ncbi.nlm.nih.gov/pubmed/30091383 http://dx.doi.org/10.2144/btn-2018-0042 |
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