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Endoplasmic reticulum retention motif fused to recombinant anti-cancer monoclonal antibody (mAb) CO17-1A affects mAb expression and plant stress response

The endoplasmic reticulum (ER) is the main site of protein synthesis, folding, and secretion to other organelles. The capacity of the ER to process proteins is limited, and excessive accumulation of unfolded and misfolded proteins can induce ER stress, which is associated with plant diseases. Here,...

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Detalles Bibliográficos
Autores principales: Song, Ilchan, Kang, YangJoo, Lee, Young Koung, Myung, Soon-Chul, Ko, Kisung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152870/
https://www.ncbi.nlm.nih.gov/pubmed/30248125
http://dx.doi.org/10.1371/journal.pone.0198978