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GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis

Starvation poses a fundamental challenge to cell survival. How autophagy promotes energy homeostasis in this setting has been extensively characterized (1), but how other mechanisms may be similarly critical is less understood. Here, we initially find that glyceraldehyde 3-phosphate dehydrogenase (G...

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Detalles Bibliográficos
Autores principales: Yang, Jia-Shu, Hsu, Jia-Wei, Park, Seung-Yeol, Li, Jian, Oldham, William M., Beznoussenko, Galina V., Mironov, Alexander A., Loscalzo, Joseph, Hsu, Victor W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152935/
https://www.ncbi.nlm.nih.gov/pubmed/30209366
http://dx.doi.org/10.1038/s41586-018-0475-6